Posted in agenda, progress on May 30, 2007 | Leave a Comment »
WASSERMAN/OUELLETTE LABORATORY
SUMMARY FORM
Name: Warren Cheung
Date: 2007-05-30
Progress
Draft of Proposal
Modularity
Setup for Entrez Gene to PubMed “muscle” subset
Other Activities
Reading
statistics – multiple testing correction, Fisher/hypergeometric distribution.
GO term analysis
MSL Poster
Goals
Complete [...]
Posted in meeting on May 18, 2007 | Leave a Comment »
Dates
1st July, 2007, final version of Manuscript completed
2 weeks before August 9 – final version sent to committee members
Proposal File format
MS Word
revisions, etc.
keep versions – use descriptive filenames w/ Datestamps
Proposal
Goals Section
This should be a concrete Mission Statement
what needs to be done
Move current “goals” to “principles” – how it will be done
layer and allow mix & [...]
Posted in agenda on May 16, 2007 | Leave a Comment »
Qualifying Exam — Thursday August 9th @ 1430-1700, at UBiC
Proposal — webpage location
Format for editing
(core?) Analysis section
Second Disease Area
Heart vs. Diabetes
vs. Cancer?
Progress: Second (and onward) degree links
via other terms (Chemical Compounds, etc.) and pathways/interactions/regulation
statistics
Posted in progress on May 11, 2007 | Leave a Comment »
Name: Warren A. Cheung
Progress
Code to download all TF genes (all species, including human)
Can generate links between genes and pubmed articles up to 3 degrees of separation
Other Activities
First Committee Meeting
Booked Qualifying Exam for Augusts 9th, Room 174 at UBiC
completed first pass of related work for proposal
Goals
generate numerical results linking genes to brain disease MeSH terms, via [...]
Posted in meeting on May 10, 2007 | Leave a Comment »
Some notes on the fallout from the committee meeting:
Avoid straying from the topic. Volunteering unnecessary/insufficiently supported information may result in further deviation from main topic and potential hot water
Related: Think before speaking. Better to take time and focus (but avoid blanking)
Expand topic to include at least one other major class of disease to take advantage of new datasets – heart, diabetes, liver – and as [...]
Posted in agenda on May 2, 2007 | Leave a Comment »
Agenda
Introductions, discuss CV
Quick overview/proposal presentation
Prototype/Preliminary results
Questions, comments, suggestions
Notes on the discussion with the committee
examine Whole Genome association studies (e.g. Parkinson’s, but also InterHeart, Diabetes) to validate genes found (in implicated loci)
For flexibility, should expand scope to include other major disease (diabetes, liver)
“haplotype”-style analysis – co-citation rate of genes
investigate textpresso-SGD link, use of UBC library literature resources
mining Patent literature – especially not well studied
investiagte rating of evidence – validation to provide quantitative measure of effectiveness of various evidence types
investigate [...]
